Hybrid polymer nanocarriers improve pulmonary mRNA vaccine delivery

An LMU research team led by Professor Olivia M. Merkel, Chair of Drug Delivery at LMU, has developed a new delivery system for inhalable mRNA vaccines. Published in the journal Cell Biomaterials, the study presents a novel combination of poly(lactic-co-glycolic acid) (PLGA) and poly(β-amino esters) (PBAEs) designed to overcome key biological barriers in the lungs.